Platelet Function Disorders
Platelets (or thrombocytes) are essential components of the blood. Along with coagulation factors, these tiny (roughly 2 – 3 µm in diameter) discoid-shaped bodies react to bleeding from blood vessel injury by clumping, thereby initiating a blood clot. In an adult, the ‘normal’ platelet count is 150 and 450 x 109/L, so there are 150,000 – …
Bleeding Disorders 101
Congenital bleeding disorders are characterised by impaired blood clotting, usually due to an inherited deficiency in or abnormal functioning of a clotting factor. There are many types (depending on which clotting factor is affected) but, with three exceptions, they are rare. The major bleeding disorders The most frequent bleeding disorders are haemophilia A, haemophilia B …